Irf1 b cell
WebNov 15, 2024 · HEK293T cells were transfected with IRF1 3 × GAS- ( a) or NLRC5 promoter-containing reporter construct ( b ), along with an empty control plasmid or with plasmids expressing the indicated... WebIRF1 and IRF2 promote the response of Th1 immune cells, whereas IRF3 and IRF7 are engaged in antibacterial and antiviral innate immunity. Expression of IRF4 and IRF8 is restricted to the lymphoid and myeloid lineages of the immune system , whereas they are crucial for B lymphocyte development and Th cell differentiation. In addition to a pro ...
Irf1 b cell
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WebApr 6, 2024 · B Higher IRF1 expression is induced when LMeC cells are infected with rNDV-cIFN ... Using KMeC and LMeC cells, we studied IRF1 expression in rNDV-infected cells. The results showed that the expression of IRF genes increased in lymphocytes co-cultured with cells infected with rNDV-cIFNγ, which suggested that cIFNγ produced after recombinant ... Web(A–B) EGF induced KPNA2 and E2F1 expression but suppressed IRF1 protein expression in lung ADC cells. A549 (A) and NCI-H460 (B) cells were cultured in the presence or absence of EGF (25 µg/mL) for the indicated times. Cell lysates were prepared and subjected to Western blotting using antibodies for the indicated proteins. β-actin was used ...
WebJan 22, 2024 · To further prove whether IRF8/IRF1 bind to CASP1 promoter in B cells, we performed ChIP experiments using chromatin prepared from EBV-postive Akata, LCL and P3HR-1 cells. Our results showed that IRF8/IRF1 indeed bind to the promoter region of CASP1 for all these cells ( S5A Fig ), suggesting that they directly regulate CASP1 …
Web(A–B) EGF induced KPNA2 and E2F1 expression but suppressed IRF1 protein expression in lung ADC cells. A549 (A) and NCI-H460 (B) cells were cultured in the presence or absence … WebNov 15, 2008 · Most importantly, IRF8 directly regulates the expression of EBF and PU.1, thereby defining novel aspects of the transcriptional regulatory network for specification …
WebNov 2, 2024 · Autophagy is an important factor in liver ischemia-reperfusion injury. In the current study we investigate the function of interferon regulatory factor-1 (IRF1) in regulating autophagy to promote hepatic ischemia reperfusion injury (IR). The high expression of IRF1 during hepatic IR exhibited increased liver damage and was associated with activation of …
Webb Western blot assay detecting IRF1 protein expression in CD11b + myeloid cells sorted from intestines of DSS-treated Carinh WT and Carinh KO mice (n = 3). c – e DSS-induced colitis model in ... ip raw socketWebThe present findings suggest that IRF1 is associated with metastasis and the degree of immune infiltration of CD8+ T cells (general), dendritic cells, T-helper 1 cells, and T cell exhaustion in COAD. These results may provide information for immunotherapy in colon cancer. 1 Introduction oramorph hypotensionWebNov 15, 2008 · The B-cell lymphoma cell line NFS-202 and subclones with siRNA-induced knockdown of IRF8 were described previously. 17 The murine follicular B-cell lymphoma cell line NFS-203 expresses little or no IRF8. Plasmids containing a full-length Irf8 cDNA (pCDNA3.1-IRF8; provided by Dr Keiko Ozato, NICHD, NIH) were transfected into NFS-203 … ip ratings lightingWebThe present findings suggest that IRF1 is associated with metastasis and the degree of immune infiltration of CD8+ T cells (general), dendritic cells, T-helper 1 cells, and T cell … ip ratings in a bathroomWebAug 1, 2024 · B16-F10 IRF1-KO cells were transduced with lentivirus prepared from pInducer20-PD-L1 and selected by G418 (800 μg/mL) to make a stable cell line. Doxycycline-induced expression of PD-L1 in B16-F10 IRF1-KO cells was confirmed by Western blot analysis. Mice and tumor models ip ratings listWebApr 11, 2024 · In all cells, around one-fifth of the regions that recruited IRF1 were within or near gene promoters, indicating that IRF1 was enriched in these regions (Figure 4 B). There were fewer (half or less) IRF1-bound regions in the part-R (H23 and H82) and non-R (H1993 and PDC11) cells, compared with the comp-R cells (A549 and Lu165). ip ratings for cell phonesWebFeb 2, 2024 · (B) IRF1 expression in primary fibroblasts from three controls (CTLs), P1, ... As in (E), B cell subclustering and cell-type annotation, together with an overlay of the patients’ and CTLs cells. (G) Proportions of each cell type expressed as a percentage of total lymphocytes. P1.1 corresponds to the first scRNA-seq analysis for P1 and P1.2 ... oramorph in elderly